If the link is proved, it could lead to the development of treatments based on the active ingredient of cannabis, tetrahydrocannabinol (THC), without its intoxicating effects.
Researchers have found that regular users of the drug had lower levels of the hormone insulin after fasting – a signal that they are protected against diabetes. They also had reduced insulin resistance. Cannabis is widely smoked in the United States with over 17 million current users of whom more than four million smoke it on a daily basis. In the UK latest figures show 2.3 million people used cannabis in the last year, but the numbers have declined in the last decade.
Two US states have recently legalised its recreational use and 19 others have legalised it for medical purposes by patients with one of several conditions including multiple sclerosis and cancer. THC has already been approved to treat the side effects of chemotherapy, nausea in cancer patients, anorexia associated with AIDS and other conditions.
The study involved almost 5,000 patients who answered a questionnaire about their drug use and were part of the National Health and Nutrition Survey between 2005 and 2010. The results showed almost 2,000 had used cannabis at some point in their lives and more than one in 10 (579) were current users. Only those who had used cannabis within the past month showed evidence of protection against diabetes, suggesting that the effects wear off in time. Current users of the drug had 16 per cent lower fasting insulin than those who had never used the drug.
Murray Mittleman, of the Cardiovascular Epidemiology Research Unit at the Beth Israel Deaconess Medical Centre in Boston, and lead author of the study published in The American Journal of Medicine, said previous studies had shown lower rates of obesity and diabetes in marijuana users.
Two previous surveys had also shown that although cannabis users consume more calories they have a lower body mass index. The mechanisms underlying this paradox are unknown, the authors say. Joseph Alpert, professor of medicine at the University of Arizona College of Medicine, Tucson, and editor in chief of the journal, said: “These are remarkable observations that are supported by basic science experiments that came to similar conclusions.
“We desperately need a great deal more basic and clinical research into the short and long term effects of marijuana in a variety of clinical settings such as cancer diabetes and frailty of the elderly.”
Almost one in 20 adults in the UK has diabetes, of which 2.6 million are diagnosed and 500,000 are undiagnosed. Rates are rising in this country and around the world, driven by Western lifestyles, and the number of cases is expected to exceed 4 million in the UK by 2025. The illness increases the risk of heart failure, kidney failure, and death – and is one of the biggest health challenges facing the UK.
By Jeremy Laurance
Cannabinoids can prevent cancer, reduce heart attacks by 66% and insulin dependent diabetes by 58%. Cannabis clinician Dr. William Courtney recommends drinking 4 – 8 ounces of raw flower and leaf juice from any Hemp plant, 5 mg of Cannabidiol (CBD) per kg of body weight, a salad of Hemp seed sprouts and 50 mg of THC taken in 5 daily doses.Cannabis – whether Sativa, Indica, Ruderalis, male, female, hermaphrodite, wild, bred for fiber, seeds or medicinal resin – is a vegetable with every dietary essential we can’t synthesize: Essential Amino Acids, Essential Fatty Acids, Essential Cannabinoid acids and hundreds of anti-Cancer compounds.Cannabis clinician Dr. William Courtney recommends drinking 4 – 8 ounces of bud and leaf juice of any Hemp plant, 5 mg of CBD per kg of body weight, a salad of Hemp seed sprouts and 50 mg of THC daily, divided into 5 doses with an Arachadonic acid source, such as Hemp seed oil.
“If you heat the plant, you will decarboxylate THC-acid and you will get high, you”ll get your 10 mg. If you don’t heat it, you can go up to five or six hundred milligrams & use it as a Dietary Cannabis. . . and push it up to the Anti-oxidant and Neuro-protective levels which come into play at hundreds of milligrams,” stated Dr. William Courtney.
“The amount of Cannabinoids we need would be difficult to get through smoked Cannabis without feeling the intoxicating effects,” said Kristen Courtney.
The Endocannabinoid System (ECS) maintains our biological systems by regulating each cell tissue. It uses Arachadonic acid/Omega 6 to make Endo-Cannabinoids: fatty molecules that communicate harm between cells. Dietary Cannabis mimics the ECS by providing Cannabinoids when there is an Arachadonic acid deficiency or Clinical Cannabinoid Deficiency.
The body regenerates best when it’s saturated with Phyto-Cannabinoids, which takes 3 months of Dietary Cannabis use.
Patients exceeding 4 decades need Dietary Cannabis daily.
Patients using blood pressure, birth control, Epilepsy, Anti-psychotic or any Cardiac medicines need more Dietary Cannabis to elevate their serum Cannabinoid levels.
Oxidative diseases and Amphetamine, radiation or Alcohol damage can be prevented or treated with Cannabinoid therapy.
Cannabinoids are particularly effective in the treatment of oxidative associated diseases of the CNS because they cross the Blood Brain Barrier and exert their anti-oxidant effects.
Hemp juice has lowered blood pressure an average of 10 points within 2 hours.
Patients suffering from end stage Cancer need to eat buds whole.
Plants sprayed with anything shouldn’t be juiced, but some pests are edible, such as Spider mites.
To prepare leaves for a juicer, avoid rinsing – soak them in water for 5 minutes.
Masticating juicers are efficient for leaves, buds and sprouts; a centrifugal juicer may need additional vegetables to chop fibers.
To preserve juice fill containers so that air is minimized; a dose of juice frozen in an ice cube tray retains medicinal value.
A sprout’s prophylactic, analgesic, anxiolytic, anti-oxidant and activities peak within 1-2 weeks.
For CBD without dysphoria from THC psycho-toxicity, heat bud to 166 degrees with a heat gun – the longer a bud is boiled, the less THC remains.
D9THC boils at 157C, D8THC boils at 175C, CBD boils at 188C.
Drinking heated juice for THC is more potent because there is less vaporization, adhesion and degradation to decrease potency.
When calculating a dose of heated juice from a new strain make sure to begin with smaller doses: the amount of THC in a cup of juice can exceed 100 joints worth – which could leave one unconscious for a number of days – and even heated leaves can be psycho-active.
A 20 mg dose of THC causes most patients to stagger, after 30 mg THC most are unable or unwilling to stand.
“The Hemp plant is actually an excellent plant because the THC content can be low, that’s if you’re treating a condition for which appears CBD food supplement is in order. . . The plants we’re using in Luxembourg have only 1% CBD, a 1% CBD plant is providing you with 19 times more CBD per pound than Oranges provide you of vitamin C. A 1% is an excellent source, you can make tremendous concentrates you can eat the plant raw – and the absence of the THC – you can heat Hemp, which you can’t do with other strains because the THC acid comes out and you end up with a psycho-toxic substance,” says Dr. William Courtney
Viable Hemp seed from the detoxyourworld, happilyraw and gojiking.co.uk websites approach pure CBD.
Steam or UV sterilized Hemp seeds sprout at a lower germination rate; such as seeds from Nuts dot com, Avian Organics and Persnickety Parrot websites.
Canadian Hemp seed oil contains 10 mg per kg of CBD; Swiss and Finland sourced Hemp seed oil can contain up to 50 mg of THC per kg.
Swiss Hemp “essential” oil contains 540 mg of CBD and 3 mg each CBD, CBG and CBN per kg with no acids.
Raw Cannabis produces non-psychoactive acidic Cannabinoids. It’s medicinal at lower doses than heated preparations because constituents have an Entourage effect when they act synergistically. 90% of the medicinal constituents are destroyed with heat – such as terpenoids, which can greatly prolong the amount of time a Cannabinoid affects our body.
“It’s the poster-child for raw food.”
Acidic Cannabinoids are absorbed by our body 400% better than neutral Cannabinoids and do not require a Cannabiniod receptor to produce medicinal activity.
Neutral Cannabinoids are the product of aging, heat or light.
THC – the only psycho-active group of Cannabinoids – and all other neutral Cannabinoids are barely present in raw Cannabis.
There 16 possible classes of Cannabinoids and over one hundred Cannabinoids in each trichome; in a ratio that changes throughout development with variations between cultivars. Each act differently: CBD-acid has anti-biotic activity but CBD doesn’t.
Contact The Humboldt Patient Resource Center, Canna Culture Collective, Leonard Moore Co-op or ask local growers in a Cannabis forum for fresh Cannabis leaves.
For more info on Cannabis, visit
Patients using blo
Rumour has it that marijuana has some pretty interesting effects on the human brain, but how could plant smoke affect our physiology? Well, it’s all to do with a case of mistaken identity. Logan Wright goes in search of cells that get duped by dope into having a high old time.
Known variously as marijuana, ganja, cannabis, pot, jays, joints and Mary Jane, the product derived from the cannabis plant is undoubtedly the most popular illicit recreational drug in the world; hence its countless pet names. It can be taken in a variety of creative ways including smoking, eating and drinking, even has incarnations in gum or brownies form.
THC, or tetrahydrocannabinol if you prefer, is a compound within the cannabis plant that, like nicotine or caffeine, may have evolved to ward off herbivores. Its strong psychoactive properties, however, have proven rather seductive to the international drugs scene.
The parts of the brain most affected by marijuana. Click to enlarge.
Once it reaches the bloodstream, THC takes only a few seconds to reach the brain, where it passes itself off as a neurotransmitter – the chemicals which carry messages between neurons in the brain. THC is shaped much like a neurotransmitter called anandamide, which means it can sneak itself into the brain’s anandamide receptor proteins and start to cause mischief. With THC’s spanner in the works, some of the brain’s normal functions really begin to waver.
The receptor proteins are located primarily in three areas of the brain: the hippocampus, responsible for short term memory; the cerebellum, an area controlling coordination; and the basal ganglia, which manages unconscious muscle movement. These are the functions that are altered by THC’s presence, which is why a marijuana user will typically experience impaired coordination, memory lapses, paranoia and altered perception, as well as feeling their heart quicken.
THC’s chemical structure. Click to enlarge. Why don’t you download the structure, draw a picture and enter it to the THC gallery?
One thing scientists do not thoroughly understand is how THC interacts with dopamine, the chemical that is well known for generating feelings of pleasure and motivation. It’s thought that when THC activates receptor proteins a signal is sent to nearby dopamine terminals in the brain. These then begin to produce inordinate amounts of dopamine, triggering that contented feeling known to so many politicians.
The health effects of marijuana are hotly contested. There is good evidence that it is effective a treating the symptoms of Parkinson’s disease and is used by many people as a treatment for a variety of ills and aches.
However, although it’s generally accepted to be safer than heroine or cocaine, marijuana may have several potential long term effects, which are less helpful. The drug has been linked to an increased incidence of schizophrenia and other mental illnesses. It is also referred to as a “gateway drug” because many marijuana users move from it to more dangerous drugs in search of a more powerful experiencer. For those particularly enamored with the drug’s effects, however, there is consolation: some believe that marijuana use may lead to an eventual perma-high.
Archaeologists have reported that marijuana was one of the first plants cultivated by humans. It was being used 10,000 years ago for linen, paper, and garments. In China and India, it was being smoked as early as 2700 BC.
The Ancient Greek historian Herodotus mentions that Scythian tribes used to pile cannabis leaves on to bonfires during wild festivals.
George Washington, the first US president, grew cannabis, declaring “Make the most you can of the Indian Hemp seed and sow it everywhere.”
In Vietnam, where cannabis grows wild and free, people rarely smoke it themselves. Instead they feed it to their pigs, who get the serious munchies. The result is that the farmers produce some very fat, and very chilled out, pigs.
via How Marijuana Works.